The NIMH website and many doctors believe titers should be elevated to indicate an active strep infection. This table indicates that often they are not elevated or only slightly elevated. This table reiterates that the best indicator is a positive strep test or a fever/sore throat event occurring 4 to 6 mos. prior to the PANDAS Acute Onset.

TITER TABLE – 2007-2009
PANDAS CASES

5/22/09

CASE

INFECTION START DATE

ACUTE
ONSET

STREP TEST

ASO-TITERS

D-NASE

#1

Boy 7

4/07 Strep w/delay of PANDAS onset
8/07 & Sinusitis

8/07

Positive 4/07

w/onset 8/07 giving a neg.
strep test

500

340 (1 yr post onset result only –
due to lab error)

#2

Girl 7

1/08 Fever/Sore Throat

2/08

3/08 Positive

28

60

Boy 8

2/07 Fever/Sore Throat

2/07

None

Normal

Normal

#3

Girl 7

10/07 Fever/Sore Throat

10/08

Negative

Normal

Normal

Boy 11

3/07 Acute Rheumatic Fever

Repairing on abx

8/08 PANDAS

7/07 & 9/07

4/08

8/08

None

None

None

1,000

Normal

200

Girl 7

11/07 Fever/Sore Throat

12/07

Negative

220

Not Given

Boy 6

6/05 Sore Throat

9/05 Strep Exposure

2/07 Sinusitis

6/05

9/05

2/07

Positive

None

None

None

Extremely High

Abx no longer work

None

#4

Boy 8

9/23/06

9/24/06

Positive

540

1,300

Boy 7

2/08

2/08

Positive

400

Negative

Boys 2, 5, 7 &
Girl 8

4 children all have PANDAS
w/Repeated Strep Infections Yearly

Immediately

Sometimes Positive
Sometimes Negative

Normal

Normal

#6

6/07 exposed to Scarlet Fever (family)

8/07

None

Normal

Normal

S

Boy 9

12/07 and 3/08 strep

3/08

Positive

100’s

100’s

S-1

Boy 6

6/07

6/07

Positive

Normal

Normal

S-2

Boy 9??

1/08

1/08

Negative

Normal

Normal

#5

Girl 9

1/08 Fever/Sore Throat

1/08

Negative

Normal

Normal

#7

Girl 7

6/06

10/08

6/06

10/08

Positive

None

800-1,000

500

None

None

#10;

Boy 11

6/08

6/08

None

202

680

Girl 6

6/08

9/08

6/08

9/08

Positive

Negative

None

None

None

None

#8

Boy 6

3/08

8/08

3/08

8/08

Positive

Positive

Normal

Normal

Normal

Normal

Girl 9

11/07 (acute catatonic state abated
w/abx)

11/07

Negative

Normal

Normal

Boy 7

11/08

11/08

Positive

Normal

Normal

Boy 9

9/08

9/08

Positive

62 (drawn only @ 6/08, 6 mos.
Post onset)

None

Girl 4

8/08—repeat strep infections for
6 mos.

Positive

5

Normal

Normal

Boy 7

11/08

11/08

Positive

1,750

1,320